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Tocris Bioscience™ LY 344864 hydrochloride
GSA_VAGREENER_CHOICE

Catalog No. 245110
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24-511-0 10 mg
24-515-0 50 mg
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Description

Potent and selective 5-HT1F agonist

Potent, selective 5-HT1F receptor agonist (EC50 = 3 nM). Displays > 80-fold selectivity over other 5-HT receptors (Ki values are 0.006, 0.53, 0.55, 0.56, 1.42, 1.70, 3.50, 3.94 and 4.85 μM for 5-HT1F, 5-HT1A, 5-HT1B, 5-HT1D, 5-HT1E, 5-HT2B, 5-HT2C, 5-HT2A and 5-HT7 receptors respectively). Inhibits neurogenic dural inflammation in vivo following i.v. and oral administration.

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Chemical Identifiers

CAS 1217756-94-9
Molecular Formula C21H23ClFN3O

Specifications

Quantity 10 mg
Formula Weight 387.88
Purity >99%
Molecular Weight (g/mol) 387.883
Chemical Name or Material LY 344864 hydrochloride

Safety and Handling

Recommended Storage Store at +4°C
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