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  5. Tocris Bioscience™ LY 450139

Tocris Bioscience™ LY 450139
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Catalog No. 655925
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Quantity:
5 mg
25 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

γ-secretase pseudo-inhibitor

LY 450139 is a γ-secretase pseudo-inhibitor. Inhibits Aβ secretion from cells in vitro and increases accumulation of γ-secretase products and long Aβ species in vitro and in vivo. Also attenuates the accumulation of activated microglia and neurological injury in a traumatic brain injury animal model.

Specifications

Chemical Name or Material (2S)-2-Hydroxy-3-methyl-N-[(1S)-1-methyl-2-oxo-2-[[(1S)-2,3,4,5-tetrahydro-3-methyl-2-oxo-1H-3-benzazepin-1-yl]amino]ethyl]butanamide
CAS 425386-60-3
Quantity 25 mg
Molecular Formula C19H27N3O4
Formula Weight 361.44
Purity 98%
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