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Ly-6C Mouse, anti-Mouse, R718, Clone: AL-21, BD Horizon™

Mouse Monoclonal Antibody

Supplier:  BD Biosciences 566987

Catalog No. BDB566987


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Description

Description

The AL-21 monoclonal antibody specifically binds to a non-polymorphic determinant of Ly-6C, a 14-17 kDa GPI-linked cell-surface antigen found on some monocyte/macrophage populations, granulocytes, endothelial cells, plasma cells, and thymocyte, NK-cell, and T-subsets. Mice with the Ly-6.2 alloantigen (eg, AKR, C57BL, C57BR, C57L, C58, DBA/2, PL, SJL, SWR, 129) have subsets of CD8+ and CD4+ Ly-6C+ T cells, while Ly-6.1 strains (eg, A, BALB/c, CBA, C3H/He, DBA/1, NZB) have only CD8+ Ly-6C+ T cells. Upregulation of Ly-6C expression on CD8+ T cells by interferons α and β and poly (I:C) has been described, and Ly-6C is a memory marker on CD8+ T cells.

TRUSTED_SUSTAINABILITY
Specifications

Specifications

Ly-6C
Monoclonal
R718
50 μg
Primary
Refrigerate Upon Arrival
Flow Cytometry
AL-21
Mouse
RUO
Mouse
Liquid
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