Invitrogen™ Ly-6E Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA575886

Catalog No. PIPA575886

Description

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Sca1, also known as Ly6A/E, is a member of the Ly6 multigene family of type V glycophosphatidylinositol anchored cell surface proteins. It is expressed on multipotent hematopoietic stem cells in bone marrow of mice with both the Ly6.1 and Ly6.2 allotypes. In the periphery, Sca1 exhibits a pattern of expression which is based on differences between the two allotypes. Ly6.1 strains (e.g., A, BALB/c, CBA, C3H/He, DBA/1, NZB) have few Sca1+ resting peripheral lymphocytes, whereas Ly6.2 strains (e.g., AKR, C57BL, C57BR, C57L, DBA/2, PL, SJL, SWR, 129) have relatively high numbers of Sca1+ lymphocytes. The expression of Sca1 is dramatically upregulated in all strains upon cellular activation.

Specifications

• Antigen: Ly-6E
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: LY6E
• Gene Alias: 9804; locus A/E; Locus AE; Ly67; Ly6A; Ly6e; ly-6E; lymphocyte antigen 6 complex, locus E; lymphocyte antigen 6E; retinoic acid induced gene E; retinoic acid-induced gene E protein; RIGE; RIG-E; SCA2; SCA-2; Stem cell antigen 2; thymic shared antigen 1; Tsa1; Tsa-1
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 17069, 362934, 4061
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q16553, Q64253
• Gene Symbols: LY6E
• Immunogen: Synthetic peptide corresponding to residues in Human Ly-6A/E.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG