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Description
The RB6-8C5 antibody reacts with a common epitope on Ly-6G and Ly-6C, previously known as the myeloid differentiation antigen Gr-1. In the bone marrow, the level of antigen expression is directly correlated with granulocyte differentiation and maturation. The antigen is also expressed on the monocyte lineage in the bone marrow, but not on erythroid cells. In the periphery, RB6-8C5 antibody recognizes granulocytes (neutrophils and eosinophils) and monocytes. The RB6-8C5 mAb is a component of the “lineage cocktail” used in studies of hematopoietic lineages. The mAb 1A8 (Cat. No. 551461) specifically recognizes Ly-6G, but not Ly-6C.
Host Species: Rat
Clone: RB6-8C5
Isotype: IgG2b κ
Species Reactivity: Mouse
Flow Cytometry
Specifications
Specifications
| Antigen | Ly-6G and Ly-6C |
| Applications | Flow Cytometry |
| Classification | Monoclonal |
| Clone | RB6-8C5 |
| Concentration | 0.2mg/mL |
| Conjugate | PerCP-Cyanine5.5 |
| Description | Ly6c, Lymphocyte antigen 6C2; Lymphocyte antigen 6G, Ly6g, Gr-1 |
| Formulation | Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide. |
| Host Species | Rat |
| Immunogen | Not Reported |
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For Research Use Only.
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