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Ly-6G and Ly-6C Rat anti-Mouse, Unlabeled, Clone: RB6-8C5, BD
Rat Monoclonal Antibody
Supplier: BD Biosciences 550291
Description
The RB6-8C5 antibody reacts with a common epitope on Ly-6G and Ly-6C, previously known as the myeloid differentiation antigen Gr-1. In the bone marrow, the level of antigen expression is directly correlated with granulocyte differentiation and maturation. The antigen is also expressed on the monocyte lineage in the bone marrow, but not on erythroid cells. In the periphery, RB6-8C5 antibody recognizes granulocytes (neutrophils and eosinophils) and monocytes. The RB6-8C5 mAb is a component of the “lineage cocktail” used in studies of hematopoietic lineages. The mAb 1A8 (Cat. No. 551461) specifically recognizes Ly-6G, but not Ly-6C. This antibody is routinely tested by immunohistochemistry. Other applications were tested at BD Biosciences Pharmingen during antibody development only or reported in the literature.
Host Species: Rat
Clone: RB6-8C5
Isotype: IgG2b κ
Species Reactivity: Mouse
Immunohistochemistry, Immunohistochemistry (Frozen)
Specifications
| Ly-6G and Ly-6C | |
| Monoclonal | |
| 0.5mg/mL | |
| Ly6c, Lymphocyte antigen 6C2; Lymphocyte antigen 6G, Ly6g, Gr-1 | |
| Rat | |
| Affinity Purified | |
| RUO | |
| Primary | |
| Store undiluted at 4°C |
| Flow Cytometry | |
| RB6-8C5 | |
| Unconjugated | |
| Aqueous buffered solution containing ≤0.09% sodium azide. | |
| Not Reported | |
| 1 mL | |
| Immunology | |
| Mouse | |
| IgG2b κ |
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Product Title
For Research Use Only.
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