LY9 Mouse anti-Human, Clone: OTI2H4, lyophilized, TrueMAB™

Mouse Monoclonal Antibody

Supplier:  OriGene CF811828

Catalog No. 50-167-0866

Description

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

CD229 (Ly9) is a cell surface receptor of the CD150 family, which includes also e.g. CD48 and CD224. Receptors of this family regulate cytokine production and cytotoxicity of lymphocytes and NK cells. High levels of CD229 are found on T and B cells, where its expression increases during their maturation. It is absent on granulocytes, bone marrow-derived dendritic cells, platelets and erythrocytes. CD229 has been also reported on mouse monocytes and NK cells. CD229 interacts homophilically through its N-terminal domain and localizes to the contact site between T cells and antigen presenting B cells during antigen-dependent immune synapse formation.

Specifications

• Antigen: LY9
• Classification: Monoclonal
• Conjugate: Unconjugated
• Gene: LY9
• Gene Alias: CD229, SLAMF3, hly9, mLY9
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 4063
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Clone: OTI2H4
• Formulation: PBS with 8% trehalose and no preservative; pH 7.3
• Gene Accession No.: Q9HBG7
• Gene Symbols: LY9
• Immunogen: Human recombit protein fragment corresponding to amino acids 48-454 of human LY9 produced in SF9 cell.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1