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Invitrogen™ LYK5 Polyclonal Antibody
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Catalog No. PIPA5115978
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100 μL
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PIPA5115978 100 μL
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Catalog No. PIPA5115978 Supplier Invitrogen™ Supplier No. PA5115978
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total STRAD.

LYK5; STE20-related Adaptor Protein (STRAD); FLJ90524. Gene Map Locus is 17q23.3 and members of STE-20 like kinase family are known to stimulate MAPK pathways by directly activating MAPKKK. STRAD is a novel pseudokinase member of this family consisting of a STE-20 like kinase domain but lacks several residues that are required for its catalytic activity. It specifically binds LKB1 and plays a key role in regulating tumor suppressor activities of LKB1. It functions as an upstream activator of LKB1 and also directs the sub-cellular localization of LKB1 by anchoring it in the cytoplasm. STRAD-LKB1 interaction results in phosphorylation of STRAD and enhanced autophosphorylation of LKB1.
TRUSTED_SUSTAINABILITY

Specifications

Antigen LYK5
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide
Gene STRADA
Gene Accession No. Q3UUJ4, Q7RTN6
Gene Alias 2610019A05Rik; 6030402H20Rik; AI480680; E130112C09Rik; LYK5; NY-BR-96; PMSE; protein kinase LYK5; serologically defined breast cancer antigen NY-BR-96; STE20-like pseudokinase; STE20-related adapter protein; STE20-related kinase adapter protein alpha; STE20-related kinase adaptor alpha; Stlk; Strad; STRAD alpha; Strada
Gene Symbols STRADA
Host Species Rabbit
Immunogen A synthesized peptide derived from human STRADA(Accession Q7RTN6), corresponding to amino acid residues M312-R362.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 72149, 92335
Target Species Human, Mouse
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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