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LYK5 Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501985781
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100 μL
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50-198-5781 100 μL
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Catalog No. 50-198-5781 Supplier Bioss Supplier No. BS3949R
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Description

Rabbit Polyclonal Antibody

LYK5; STE20-related Adaptor Protein (STRAD); FLJ90524. Gene Map Locus is 17q23.3 and members of STE-20 like kinase family are known to stimulate MAPK pathways by directly activating MAPKKK. STRAD is a novel pseudokinase member of this family consisting of a STE-20 like kinase domain but lacks several residues that are required for its catalytic activity. It specifically binds LKB1 and plays a key role in regulating tumor suppressor activities of LKB1. It functions as an upstream activator of LKB1 and also directs the sub-cellular localization of LKB1 by anchoring it in the cytoplasm. STRAD-LKB1 interaction results in phosphorylation of STRAD and enhanced autophosphorylation of LKB1.

Specifications

Antigen LYK5
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene STRADA
Gene Accession No. Q7RTN6
Gene Alias 2610019A05Rik; 6030402H20Rik; AI480680; E130112C09Rik; LYK5; NY-BR-96; PMSE; protein kinase LYK5; Serologically defined breast cancer antigen NY-BR-96; STE20-like pseudokinase; STE20-related adapter protein; STE20-related kinase adapter protein alpha; STE20-related kinase adaptor alpha; Stlk; STRAD; STRAD alpha; Strada
Gene Symbols STRADA
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human LYK5.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 92335
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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