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Invitrogen™ Lyn Polyclonal Antibody
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Catalog No. PIPA581925
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100 μL
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PIPA581925 100 μL
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Catalog No. PIPA581925 Supplier Invitrogen™ Supplier No. PA581925
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: KGKDSLSDDG VDLKTQPVRN TERTIYVRDP TSNKQQRPVP ESQLLPGQRF QTKDPEEQGD IVVALYPYDG IHPDDLSFKK GEKMKVLEEH GEWWKAKSLL TKKEGFIPSN YVAKLNTLET EEWFFKDITR KDAERQLLAP G Highest antigen sequence indentity to the following orthologs: Rat - 93%, Mouse - 91%.

Lyn proto oncogene (Lcl/Yes related novel protein tyrosine kinase) is encoded by the Lyn gene located on chromosome 8 in humans and belongs to the Src family kinase. It is a non-receptor tyrosine kinase that acts as a mediator in transducing cellular signaling. The most well studied expression of Lyn is in hematopoietic cell types, both lymphoid and myeloid cells with exclusion in T lymphocytes. It has also been observed that Lyn plays diverse roles such as in regulation of B cell receptor signaling, mast cell signaling and Epithelial - Mesenchymal Transition (EMT).
TRUSTED_SUSTAINABILITY

Specifications

Antigen Lyn
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene LYN
Gene Accession No. P07948, P25911, Q07014
Gene Alias AA407514; CD180; CD180 antigen; CD180 molecule; CH73-38P6.3; FLJ26625; Hck-2; JTK8; lck/Yes-related novel protein tyrosine kinase; LY64; Ly78; lymphocyte antigen 64; lymphocyte antigen-64, radioprotective, 105kDa; LYN; lyn protein non-receptor kinase; lyn protein tyrosine kinase; LYN proto-oncogene, Src family tyrosine kinase; p53Lyn; p56Lyn; Radioprotective 105 kDa protein; RP105; Tyrosine-protein kinase Lyn; v-yes-1 Yamaguchi sarcoma viral related oncogene homolog; v-yes-1 Yamaguchi sarcoma viral related oncogene protein-like protein; Yamaguchi sarcoma viral (v-yes-1) oncogene homolog; zgc:92124
Gene Symbols LYN
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human LYN. Recombinant protein control fragment (Product #RP-95925).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 17096, 4067, 81515
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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