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Invitrogen™ Lypd3 Polyclonal Antibody
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Catalog No. PIPA548085
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100 μg
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PIPA548085 100 μg
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Catalog No. PIPA548085 Supplier Invitrogen™ Supplier No. PA548085
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Description

Goat Polyclonal Antibody

In direct ELISAs, approximately 40% cross-reactivity with recombinant human C4.4A is observed. Reconstitute at 0.2 mg/mL in sterile PBS.

Lymphocyte antigen 6 family member D3 (LYPD3), also known as C4.4A, is a gene located on chromosome 19q13.11 that encodes a glycosylphosphatidylinositol (GPI)-anchored protein belonging to the Ly6/uPAR superfamily. LYPD3 is expressed in various epithelial tissues and is implicated in cellular adhesion and migration processes. The protein plays a significant role in tumor progression and metastasis, with its expression being notably upregulated in several cancers, including squamous cell carcinoma and lung cancer. LYPD3 contributes to the invasive behavior of cancer cells by interacting with matrix components and modulating signaling pathways related to cell motility and adhesion. Its involvement in cancer biology makes LYPD3 a potential biomarker for tumor aggressiveness and a target for therapeutic intervention aimed at inhibiting cancer cell dissemination. Research continues to explore its functional mechanisms in oncogenesis and potential applications in cancer treatment strategies.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Lypd3
Applications Immunohistochemistry (Frozen), Western Blot
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 5% trehalose and No Preservative
Gene LYPD3
Gene Accession No. Q91YK8
Gene Alias 2310061G07Rik; C4.4A; GPI-anchored metastasis-associated protein C4.4A homolog; GPI-anchored metastasis-associated protein homolog; LY6/PLAUR domain containing 3; ly6/PLAUR domain-containing protein 3; LYPD3; Matrigel-induced gene C4 protein; MIG-C4; UNQ491/PRO1007
Gene Symbols LYPD3
Host Species Goat
Immunogen Mouse myeloma cell line NS0-derived recombinant mouse C4.4A Leu33-His287.
Purification Method Antigen Affinity Chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 72434
Target Species Mouse
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Lyophilized
Isotype IgG
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