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Invitrogen™ LYPD3 Polyclonal Antibody
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Catalog No. PIPA532908
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50 μg
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PIPA532908 50 μg
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Catalog No. PIPA532908 Supplier Invitrogen™ Supplier No. PA532908
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Description

Rabbit Polyclonal Antibody

Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Dog, Elephant, Horse, Rabbit (100%) Marmoset, Mouse, Rat, Panda, Pig (93%) Bovine (86%).

Lymphocyte antigen 6 family member D3 (LYPD3), also known as C4.4A, is a gene located on chromosome 19q13.11 that encodes a glycosylphosphatidylinositol (GPI)-anchored protein belonging to the Ly6/uPAR superfamily. LYPD3 is expressed in various epithelial tissues and is implicated in cellular adhesion and migration processes. The protein plays a significant role in tumor progression and metastasis, with its expression being notably upregulated in several cancers, including squamous cell carcinoma and lung cancer. LYPD3 contributes to the invasive behavior of cancer cells by interacting with matrix components and modulating signaling pathways related to cell motility and adhesion. Its involvement in cancer biology makes LYPD3 a potential biomarker for tumor aggressiveness and a target for therapeutic intervention aimed at inhibiting cancer cell dissemination. Research continues to explore its functional mechanisms in oncogenesis and potential applications in cancer treatment strategies.
TRUSTED_SUSTAINABILITY

Specifications

Antigen LYPD3
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.1% sodium azide
Gene LYPD3
Gene Accession No. O95274
Gene Alias 2310061G07Rik; C4.4A; GPI-anchored metastasis-associated protein C4.4A homolog; GPI-anchored metastasis-associated protein homolog; LY6/PLAUR domain containing 3; ly6/PLAUR domain-containing protein 3; LYPD3; Matrigel-induced gene C4 protein; MIG-C4; UNQ491/PRO1007
Gene Symbols LYPD3
Host Species Rabbit
Immunogen Synthetic 14 amino acid peptide from N-terminus of human LYPD3.
Purification Method Antigen affinity chromatography
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 100070126, 100339878, 27076, 484471
Target Species Human, Canine, Rabbit, Horse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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