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LYPLA3 Polyclonal Antibody, Invitrogen™

Catalog No. PIPA531700
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PIPA531700 100 μL
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Catalog No. PIPA531700 Supplier Thermo Scientific Supplier No. PA531700

Description

Rabbit Polyclonal Antibody

Recommended positive controls: HepG2. Predicted reactivity: Mouse (88%), Rat (87%), Dog (89%), Rhesus Monkey (97%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Lysophospholipases are enzymes that act on biological membranes to regulate the multifunctional lysophospholipids. The protein encoded by this gene hydrolyzes lysophosphatidylcholine to glycerophosphorylcholine and a free fatty acid. This enzyme is present in the plasma and thought to be associated with high-density lipoprotein. A later paper contradicts the function of this gene. It demonstrates that this gene encodes a lysosomal enzyme instead of a lysophospholipase and has both calcium-independent phospholipase A2 and transacylase activities.
TRUSTED_SUSTAINABILITY

Specifications

Antigen LYPLA3
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7
Gene PLA2G15
Gene Accession No. Q8NCC3
Gene Alias 1-O-acylceramide synthase; 1-O-acylceramide synthase {ECO:0000303; 1-O-acylceramidesynthase; ACS; ACS {ECO:0000303; C87498; EMBL:AAH98894.1}; EMBL:AAS66767.1}; Ensembl:ENSRNOP00000026996, ECO:0000312; Group XV phospholipase A2; group XV phospholipase A2 {ECO:0000312; GXVPLA2; LCAT-like lysophospholipase; LCAT-like lysophospholipase {ECO:0000250; LLPL; LLPL {ECO:0000250; LPLA2; LPLA2 {ECO:0000303; LYPLA3; Lysophospholipase 3; lysophospholipase 3 (lysosomal phospholipase A2); lysophospholipase 3 {ECO:0000250; lysosomal phospholipase A2; lysosomal phospholipase A2 {ECO:0000303; phospholipase A2 group XV; phospholipase A2, group XV; PLA2G15; pla2g15 {ECO:0000312; PubMed:15294901, ECO:0000312; PubMed:15294901}; RGD:1302982}; UniProtKB:Q8VEB4}; UNQ341/PRO540
Gene Symbols PLA2G15
Host Species Rabbit
Immunogen Recombinant fragment corresponding to a region within amino acids 224 and 412 of Human LYPLA3
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 23659
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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