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Lysyl tRNA synthetase Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501987066
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50-198-7066 100 μL
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Catalog No. 50-198-7066 Supplier Bioss Supplier No. BS6127R
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Description

Rabbit Polyclonal Antibody

Syk is a cytoplasmic protein tyrosine kinase that translocates to the plasma membrane upon B cell antigen receptor (BCR) or the high-affinity IgE receptor (FcepsilonRI) triggering, and phosphorylates downstream adaptor proteins, thereby providing docking sites for initiation of subsequent signaling pathways, such as calcium mobilization, cytoskeleton remodeling, or transcription of specific genes. Syk binds to the receptor assemblies through interactions of its pair of SH2 domains with ITAM motives of the receptor, which have been phosphorylated by Src-family kinases. These kinases also help to activate Syk by phosphorylation of its activation loop.

Specifications

Antigen Lysyl tRNA synthetase
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Syk
Gene Accession No. P43405
Gene Alias DKFZp313N1010; EC 2.7.10.2; FLJ25043; FLJ37489; HGNC:11205; kinase Syk; KSYK; p72Syk; p72-Syk; ptk72; SP1; spleen associated tyrosine kinase; Spleen tyrosine kinase; Syk; Sykb; Tyrosine-protein kinase SYK
Gene Symbols Syk
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human KARS2/Lysyl tRNA syntase.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 6850
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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