Invitrogen™ LZIP Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5121011

Catalog No. PIPA5121011

Description

Positive test controls include: Jurkat, HeLa, 293T, HepG2, Mouse brain, Mouse liver, Mouse pancreas. The target is usually found in the following locations: Cytoplasm, Endoplasmic reticulum membrane, Membrane, Nucleus, Single-pass type II membrane protein. Immunogen sequence: MELELDAGDQ DLLAFLLEES GDLGTAPDEA VRAPLDWALP LSEVPSDWEV DDLLCSLLSP PASLNILSSS NPCLVHHDHT YSLPRETVSM DLESESCRKE GTQMTPQHME ELAEQEIARL VLTDEEKSLL EKEGLILPET LPLTKTEEQI LKRVRRKIRN KRSAQESRRK KKVYVGGLES RVLKYTAQNM ELQNKVQLLE EQNLSLLDQL RKLQAMVIEI SNKTSSSSTC.

This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds to the cAMP-responsive element, an octameric palindrome. The protein interacts with host cell factor C1, which also associates with the herpes simplex virus (HSV) protein VP16 that induces transcription of HSV immediate-early genes. This protein and VP16 both bind to the same site on host cell factor C1. It is thought that the interaction between this protein and host cell factor C1 plays a role in the establishment of latency during HSV infection. An additional transcript variant has been identified, but its biological validity has not been determined.

Specifications

• Antigen: LZIP
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CREB3
• Gene Alias: AU044960; AW538053; basic leucine zipper protein; C80076; cAMP responsive element binding protein 3; cAMP-responsive element-binding protein 3; CREB3; CREB-3; cyclic AMP response element (CRE)-binding protein/activating transcription factor 1; cyclic AMP-responsive element-binding protein 3; leucin zipper proitein; Leucine zipper protein; Luman; LZIP; LZIP-1; LZIP-2; N-terminal Luman; Processed cyclic AMP-responsive element-binding protein 3; sLZIP; small leucine zipper protein; transcription factor LZIP; transcription factor LZIP-alpha
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 10488, 12913, 298400
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot, Immunocytochemistry
• Concentration: 2.24 mg/mL
• Formulation: PBS with 50% glycerol and 0.05% ProClin 300; pH 7.3
• Gene Accession No.: O43889, Q61817
• Gene Symbols: CREB3
• Immunogen: Recombinant Protein (or fragment).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG