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Invitrogen™ LZK Polyclonal Antibody
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Catalog No. PIPA587700
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100 μL
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PIPA587700 100 μL
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Catalog No. PIPA587700 Supplier Invitrogen™ Supplier No. PA587700
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: CWRSSEPDKG QAGPWGCCQA DAYDPCLQCR PEQYGSLDIP SAEPVGRSPD LSKSPAHNPL LENAQSSEKT EENEFSGCRS ESSLGTSHLG TPPALPRKTR PLQKSGDDSS EEEEGEVDSE VEFPRRQRPH RCISSCQSYS TFSSENFSVS DGEEGNTSDH SNSPDELADK LEDRLAEKLD DLLSQTPEIP IDISSHSDGL SDKECAVRRV KTQMSLGKLC VEERGYENPM QFEESDCDSS DGECSDATVR TNKHYSSATW; Positive Samples: BxPC-3, U-87MG, LO2, BT-474, Mouse kidney, Mouse pancreas; Cellular Location: Cytoplasm, Membrane, Peripheral membrane protein.

Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The tyrosine-like kinase (TLK) group consists of 40 tyrosine and serine-threonine kinases such as MLK (mixed-lineage kinase), LISK (LIMK/TESK), IRAK (interleukin-1 receptor-associated kinase), Raf, RIPK (receptor-interacting protein kinase), and STRK (activin and TGF-beta receptors) families.
TRUSTED_SUSTAINABILITY

Specifications

Antigen LZK
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 2.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene MAP3K13
Gene Accession No. O43283, Q1HKZ5
Gene Alias C130026N12Rik; Leucine zipper-bearing kinase; LZK; Map3k13; MEKK13; mitogen activated protein kinase kinase kinase 13; mitogen-activated protein kinase kinase kinase 13; Mixed lineage kinase; MLK
Gene Symbols MAP3K13
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 500-759 of human MAP3K13 (NP_0012292461).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 71751, 9175
Target Species Human, Mouse
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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