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Invitrogen™ LZTR2 Polyclonal Antibody
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Catalog No. PIPA531838
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100 μL
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Catalog No. Quantity
PIPA531838 100 μL
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Catalog No. PIPA531838 Supplier Invitrogen™ Supplier No. PA531838
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Description

Rabbit Polyclonal Antibody

Recommended positive controls: A549, HeLa. Predicted reactivity: Human (99%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

LZTR2, also known as RGPR-p117, is a member of the BTB-kelch superfamily and was initially described as a nuclear factor I (NFI) binding protein and transcriptional regulator of the regucalcin gene. LZTR2 is cytoplasmically localized but is thought to translocate to the nucleus, a process mediated by protein kinase C signaling following hormonal stimulation. Recent evidence has suggested that there is a strong correlation of single nucleotide polymorphisms of LZTR2 with obesity in the Japanese population similar to that seen with the TMEM18 gene and the GNPDA2, BDNF, FAIM2, and MC4R genes with obesity in Caucasian populations, suggesting LZTR2 may play a role in metabolism and obesity risk.
TRUSTED_SUSTAINABILITY

Specifications

Antigen LZTR2
Applications Western Blot
Classification Polyclonal
Concentration 0.74 mg/mL
Conjugate Unconjugated
Formulation 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
Gene SEC16B
Gene Accession No. Q96JE7
Gene Alias KIAA1928; Leucine zipper transcription regulator 2; LZTR2; PGPR-p117; protein SEC16 homolog B; protein transport protein Sec16B; Regucalcin gene promoter region-related protein p117; regucalcin gene promotor region related protein; RGPR; Rgpr-p117; SEC16 homolog B; SEC16 homolog B (S. cerevisiae); SEC16 homolog B, endoplasmic reticulum export factor; Sec16b; SEC16S
Gene Symbols SEC16B
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the center region of human LZTR2. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 89866
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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