Invitrogen™ LZTR2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA578613

Catalog No. PIPA578613

Description

Predicted Reactivity: Human (100%), Rat (84%), Rabbit (90%), Bovine (92%) Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

LZTR2, also known as RGPR-p117, is a member of the BTB-kelch superfamily and was initially described as a nuclear factor I (NFI) binding protein and transcriptional regulator of the regucalcin gene. LZTR2 is cytoplasmically localized but is thought to translocate to the nucleus, a process mediated by protein kinase C signaling following hormonal stimulation. Recent evidence has suggested that there is a strong correlation of single nucleotide polymorphisms of LZTR2 with obesity in the Japanese population similar to that seen with the TMEM18 gene and the GNPDA2, BDNF, FAIM2, and MC4R genes with obesity in Caucasian populations, suggesting LZTR2 may play a role in metabolism and obesity risk.

Specifications

• Antigen: LZTR2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SEC16B
• Gene Alias: KIAA1928; Leucine zipper transcription regulator 2; LZTR2; PGPR-p117; protein SEC16 homolog B; protein transport protein Sec16B; Regucalcin gene promoter region-related protein p117; regucalcin gene promotor region related protein; RGPR; Rgpr-p117; SEC16 homolog B; SEC16 homolog B (S. cerevisiae); SEC16 homolog B, endoplasmic reticulum export factor; Sec16b; SEC16S
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 89866, 89867
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 1 mg/mL
• Formulation: 0.1M tris glycine with 20% glycerol, 0.1M glycine and 0.01% thimerosal; pH 7
• Gene Accession No.: Q91XT4, Q96JE7
• Gene Symbols: SEC16B
• Immunogen: Recombinant protein encompassing a sequence within the center region of human LZTR2. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG