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Invitrogen™ LZTR2 Polyclonal Antibody
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Catalog No. PIPA584911
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100 μL
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PIPA584911 100 μL
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Catalog No. PIPA584911 Supplier Invitrogen™ Supplier No. PA584911
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: VPETHLPGTG SSVAVTEATG GTVWEEMLQT HLGPGENTVS QETSQPPDGQ EVISKPQTPL AARPRSISES SASSAKEDEK ESSDE Highest antigen sequence indentity to the following orthologs: Rat - 62%, Mouse - 60%.

LZTR2, also known as RGPR-p117, is a member of the BTB-kelch superfamily and was initially described as a nuclear factor I (NFI) binding protein and transcriptional regulator of the regucalcin gene. LZTR2 is cytoplasmically localized but is thought to translocate to the nucleus, a process mediated by protein kinase C signaling following hormonal stimulation. Recent evidence has suggested that there is a strong correlation of single nucleotide polymorphisms of LZTR2 with obesity in the Japanese population similar to that seen with the TMEM18 gene and the GNPDA2, BDNF, FAIM2, and MC4R genes with obesity in Caucasian populations, suggesting LZTR2 may play a role in metabolism and obesity risk.
TRUSTED_SUSTAINABILITY

Specifications

Antigen LZTR2
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene SEC16B
Gene Accession No. Q96JE7
Gene Alias KIAA1928; Leucine zipper transcription regulator 2; LZTR2; PGPR-p117; protein SEC16 homolog B; protein transport protein Sec16B; Regucalcin gene promoter region-related protein p117; regucalcin gene promotor region related protein; RGPR; Rgpr-p117; SEC16 homolog B; SEC16 homolog B (S. cerevisiae); SEC16 homolog B, endoplasmic reticulum export factor; Sec16b; SEC16S
Gene Symbols SEC16B
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human SEC16B. Recombinant protein control fragment (Product #RP-108259).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 89866
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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