Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More

Invitrogen™ M-cadherin Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5106546

Catalog No. PIPA5106546


Only null left
Add to Cart

Description

Description

Antibody detects endogenous levels of total CDH15.

Cadherins are a multigene family of Ca++-dependent cell adhesion molecules. They are transmembrane glycoproteins consisting of an extracellular domain, which mediates Ca++-dependent intercellular adhesion by homophilic interactions, a transmembrane region and a cytoplasmic domain. The extracellular domain is divided into a series of subdomains designated EC1-EC5. Homolgies between different members of the cadherin family are most prominent in the cytoplasmic domain and in EC1 and EC2 and much less so in EC5 of the extracellular domain and in the transmembrane region. The binding properties and specificities of the adhesive function are located in the N-terminal part of the molecules. Four members of the cadherin family have been identified and molecularly cloned from mammalian cells. These include the neuronal (N), epithelial (E), placental (P) and muscle (M) cadherins. M-cadherin is not found in fibroblasts but is expressed at low level in myoblasts and is upregulated following induction of myotube formation, suggesting a specific function in skeletal muscle cell differentiation.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

M-cadherin
Polyclonal
Unconjugated
CDH15
AI323380; cadherin 15; cadherin 15, type 1, M-cadherin (myotubule); cadherin-14; Cadherin-15; cadherin-3; Cdh14; Cdh15; CDH3; CDHM; CRSBP-1; HAR; LYVE-1; M cadherin; Mcad; M-cadherin; MRD3; Muscle cadherin; muscle-cadherin; XLKD1
Rabbit
Affinity chromatography
RUO
1013, 12555, 361432
-20°C
Liquid
Western Blot, Immunocytochemistry
1 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
P33146, P55291
CDH15
A synthesized peptide derived from human CDH15(Accession P55291), corresponding to amino acid residues D88-L138.
100 μL
Primary
Human, Mouse, Rat
Antibody
IgG
Product Suggestions

Product Suggestions

Videos
SDS
Documents

Documents

Product Certifications
Promotions

Promotions

Product Content Correction

Your input is important to us. Please complete this form to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Your feedback has been submitted: Thank you for helping us improve our website.