M Cadherin Rabbit anti-Human, Polyclonal, Bioss

Catalog No.	Quantity
50-198-7424	100 μL

Catalog No. 50-198-7424 Supplier Bioss Supplier No. BS6678R

Description

Rabbit Polyclonal Antibody

Cadherins are a multigene family of Ca++-dependent cell adhesion molecules. They are transmembrane glycoproteins consisting of an extracellular domain, which mediates Ca++-dependent intercellular adhesion by homophilic interactions, a transmembrane region and a cytoplasmic domain. The extracellular domain is divided into a series of subdomains designated EC1-EC5. Homolgies between different members of the cadherin family are most prominent in the cytoplasmic domain and in EC1 and EC2 and much less so in EC5 of the extracellular domain and in the transmembrane region. The binding properties and specificities of the adhesive function are located in the N-terminal part of the molecules. Four members of the cadherin family have been identified and molecularly cloned from mammalian cells. These include the neuronal (N), epithelial (E), placental (P) and muscle (M) cadherins. M-cadherin is not found in fibroblasts but is expressed at low level in myoblasts and is upregulated following induction of myotube formation, suggesting a specific function in skeletal muscle cell differentiation.

Specifications

• Antigen: M Cadherin
• Applications: Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Classification: Polyclonal
• Concentration: 1 μg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
• Gene: CDH15
• Gene Accession No.: P55291
• Gene Alias: AI323380; cadherin 15; cadherin 15, type 1, M-cadherin (myotubule); Cadherin-14; Cadherin-15; cadherin-3; Cdh14; Cdh15; CDH3; CDHM; CRSBP-1; HAR; LYVE-1; M cadherin; MCAD; M-cadherin; MRD3; Muscle cadherin; muscle-cadherin; XLKD1
• Gene Symbols: CDH15
• Host Species: Rabbit
• Immunogen: KLH conjugated synthetic peptide derived from human M-Cadherin.
• Purification Method: Protein A
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 1013
• Target Species: Human
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG