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Tocris Bioscience™ M62812

Catalog No. 570510
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57-051-0 10mg
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Catalog No. 57-051-0 Supplier Tocris Bioscience™ Supplier No. 5705/10
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Description

TLR-4 inhibitor

M62812 is a TLR4 inhibitor. Inhibits LPS-induced NF-κB activation in HEK293 cells (IC50 = 2.4 μg/mL). Also inhibits LPS-induced cytokine production and procoagulant effects in PBMCs and HUVECs. Prolongs survival in a mouse septic shock model.

Specifications

Chemical Name or Material 6-(2-Aminophenoxy)-1,2-benzisothiazol-3-amine dihydrochloride
CAS 613263-00-6
Assay Percent Range >98%
Quantity 10 mg
Molecular Formula C13H11N3OS.2HCl
Formula Weight Observed MW: 330.23
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