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  5. Tocris Bioscience™ M8 B hydrochloride

Tocris Bioscience™ M8 B hydrochloride
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Catalog No. 532410
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Catalog No. Quantity
53-241-0 10 mg
53-245-0 50 mg
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Catalog No. 53-241-0 Supplier Tocris Bioscience™ Supplier No. 5324/10
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Description

Potent and selective TRPM8 channel blocker

M8 B hydrochloride is a potent and selective TRPM8 channel blocker. Blocks cold- and icilin -induced TRPM8 activation in vitro (IC50 values are 7.8 and 26.9 nM respectively). Exhibits no effect at other TRP channels (IC50 > 20 μM). Reduces body temperature in vivo.

Specifications

Quantity 10 mg
Product Type M8 B hydrochloride
Purity >99%
Molecular Weight (g/mol) 432.96
Inhibitors M8 B hydrochloride

For Research Use Only

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