Tocris™ M8 B hydrochloride

Potent and selective TRPM8 channel blocker

Manufacturer: Tocris™ 5324/50

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Catalog No. 53-245-0

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For Research Use Only


    Specifications

    Product Type M8 B hydrochloride
    Inhibitors M8 B hydrochloride
    Purity >99
    Molecular Weight 432.96
    Quantity 50mg

    Potent and selective TRPM8 channel blocker. Blocks cold- and icilin-induced TRPM8 activation in vitro (IC50 values are 7.8 and 26.9nM respectively). Exhibits no effect at other TRP channels (IC50 > 20µM). Reduces body temperature in vivo.

    • Chemical Name: N-(2-Aminoethyl)-N-[[3-methoxy-4-(phenylmethoxy)phenyl]methyl]-2-thiophenecarboxamide hydrochloride
    • Formula: C22H24N2O3S.HCl
    • CAS Number: 883976-12-3
    • Solubility: Soluble to 10mM in water with sonication and to 100mM in DMSO
    • Purity: >99

  • Description & Specifications

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