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MACF1 Rabbit anti-Human, Mouse, Polyclonal, Bethyl Laboratories

Catalog No. 501568053
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50-156-8053 100 μL
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Catalog No. 50-156-8053 Supplier Bethyl Laboratories, Inc Supplier No. A304564A
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Description

Rabbit Polyclonal Antibody

The recommended shelf life for this product is 1 year from date of receipt.

Isoform 2 is a F-actin-binding protein which may play a role in cross-linking actin to other cytoskeletal proteins and also binds to microtubules. Plays an important role in ERBB2-dependent stabilization of microtubules at the cell cortex. Acts as a positive regulator of Wnt receptor signaling pathway and is involved in the translocation of AXIN1 and its associated complex (composed of APC, CTNNB1 and GSK3B) from the cytoplasm to the cell membrane. Has actin-regulated ATPase activity and is essential for controlling focal adhesions (FAs) assembly and dynamics. May play role in delivery of transport vesicles containing GPI-linked proteins from the trans-Golgi network through its interaction with GOLGA4. Plays a key role in wound healing and epidermal cell migration. Required for efficient upward migration of bulge cells in response to wounding and this function is primarily rooted in its ability to coordinate MT dynamics and polarize hair follicle stem cells.

Specifications

Antigen MACF1
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/ml
Conjugate Unconjugated
Formulation phosphate, tris citrate with 0.09% sodium azide; pH 7-8
Gene MACF1
Gene Accession No. Q9QXZ0, Q9UPN3
Gene Alias 620 kDa actin binding protein, 620 kDa actin-binding protein, ABP620, ACF7, actin cross-linking factor, actin cross-linking family protein 7, FLJ45612, FLJ46776, KIAA0465, KIAA1251, MACF, macrophin 1, macrophin 1 isoform, Macrophin-1, OFC4, trabeculin-alpha
Gene Symbols MACF1
Host Species Rabbit
Immunogen Between 1975 and 2025
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 11426, 23499
Target Species Human, Mouse
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG
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