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Invitrogen™ Macro H2A.2 Polyclonal Antibody
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Catalog No. PIPA530648
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100 μL
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PIPA530648 100 μL
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Catalog No. PIPA530648 Supplier Invitrogen™ Supplier No. PA530648
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Description

Rabbit Polyclonal Antibody

Recommended positive controls: mouse brain, human H2AFY2-transfected 293T. Predicted reactivity: Mouse (99%), Rat (99%), Xenopus laevis (84%), Chicken (95%), Rhesus Monkey (100%), Bovine (100%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Variant histone H2A which replaces conventional H2A in a subset of nucleosomes where it represses transcription. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. May be involved in stable X chromosome inactivation.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Macro H2A.2
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7
Gene H2AFY2
Gene Accession No. Q8CCK0, Q9P0M6
Gene Alias Core histone macro-H2A.2; core histone macroH2A2.2; H2A histone family member Y2; H2A histone family, member Y2; H2AFY2; H2afy3; Histone macroH2A2; histone mH2A2; macroH2A2; mH2A2; RGD1561371
Gene Symbols H2AFY2
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the center region of human Macro H2A.2. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 404634, 55506
Target Species Human, Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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