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Invitrogen™ Macro H2A.2 Polyclonal Antibody
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Catalog No. PIPA5116340
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400 μL
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PIPA5116340 400 μL
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Catalog No. PIPA5116340 Supplier Invitrogen™ Supplier No. PA5116340
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Description

Rabbit Polyclonal Antibody

Macro H2A.2 Polyclonal Antibody for Western Blot

Variant histone H2A which replaces conventional H2A in a subset of nucleosomes where it represses transcription. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. May be involved in stable X chromosome inactivation.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Macro H2A.2
Applications Western Blot
Classification Polyclonal
Conjugate Unconjugated
Formulation PBS with 0.09% sodium azide; pH 7.4
Gene H2AFY2
Gene Accession No. Q9P0M6
Gene Alias Core histone macro-H2A.2; core histone macroH2A2.2; H2A histone family member Y2; H2A histone family, member Y2; H2AFY2; H2afy3; Histone macroH2A2; histone mH2A2; macroH2A2; mH2A2; RGD1561371
Gene Symbols H2AFY2
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide between 148-169 amino acids from the Central region of human H2AFY2.
Purification Method Antigen affinity chromatography, Protein A
Quantity 400 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 55506
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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