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Invitrogen™ Macrophages/Monocytes Monoclonal Antibody (ER-HR3)
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Catalog No. 01676515
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100 μg
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Catalog No. Quantity
01-676-515 100 μg
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Catalog No. 01-676-515 Supplier Invitrogen™ Supplier No. MA140078
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Description

Rat Monoclonal Antibody

MA1-40078 detects Monocytes/Macrophages from mouse samples. MA1-40078 is specially reactive to the monocytes and macrophages located in hemopoietic organs. Whereas all other leukocytes are ER-HR3 negative, up to 70% of circulating monocytes stain positive with this monoclonal antibody. Furthermore, about 30% of bone marrow cells express the antigen. Other positive macrophages can be found in the splenic red pulp, in the mesenteric lymphoid paracortex, interfollicular areas of Peyer's patches and bone marrow. Few positive cells are observed in the thymic cortex and the connective tissues of the gastro-intestinal tract, the dermis and the renal medulla. Epidermal Langerhans cells also express the antigen. MA1-40078 has been successfully used in immunohistochemistry (paraffin and frozen) and flow cytometry applications. The MA1-40078 immunogen is mouse monocytes and macrophages.

Macrophages are a large phagocytic cell found in stationary form in the tissues or as a mobile white blood cell, especially at sites of infection. Monocytes are a large phagocytic white blood cell with a simple oval nucleus and clear, grayish cytoplasm. Monocytes and macrophages are found in interdigitating cells and activated microglia cells.
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Specifications

Antigen Macrophages/Monocytes
Applications Flow Cytometry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin)
Classification Monoclonal
Clone ER-HR3
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.1% BSA and 0.02% sodium azide
Gene Alias Macrophage; Monocyte
Host Species Rat
Immunogen Murine monocytes and macrophages.
Purification Method Protein G
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Target Species Mouse
Content And Storage 4°C
Product Type Antibody
Form Liquid
Isotype IgG2c
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Safety and Handling

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