Invitrogen™ MAD4 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5119837

Catalog No. PIPA5119837

Description

Positive Control: Mouse brain tissue lysate, mouse lung tissue lysate. Subcellular Location: Nucleus.

This gene is a member of the MAD gene family. The MAD genes encode basic helix-loop-helix-leucine zipper proteins that heterodimerize with MAX protein, forming a transcriptional repression complex. The MAD proteins compete for MAX binding with MYC, which heterodimerizes with MAX forming a transcriptional activation complex. Studies in rodents suggest that the MAD genes are tumor suppressors and contribute to the regulation of cell growth in differentiating tissues.

Specifications

• Antigen: MAD4
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: MXD4
• Gene Alias: 2810410A03Rik; bHLHc12; Class C basic helix-loop-helix protein 12; LOW QUALITY PROTEIN: max dimerization protein 4; MAD4; Mad4 homolog; max dimerization protein 4; Max dimerizer 4; max-associated protein 4; Max-interacting transcriptional repressor MAD4; MST149; MSTP149; MXD4
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 10608, 17122
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: TBS with 0.2% BSA, 50% glycerol and 0.05% sodium azide; pH 7.4
• Gene Accession No.: Q14582, Q60948
• Gene Symbols: MXD4
• Immunogen: Recombinant protein within human MAD4 aa 1-180.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG