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Description
The protein encoded by this gene is an endothelial cell adhesion molecule that interacts preferentially with the leukocyte beta7 integrin LPAM-1 (alpha4beta7), L-selectin, and VLA-4 (alpha4beta1) on myeloid cells to direct leukocytes into mucosal and inflamed tissues. It is a member of the immunoglobulin family and is similar to ICAM1 and VCAM1. At least seven alternatively spliced transcripts encoding different protein isoforms have been found for this gene, but the full-length nature of some variants has not been determined. [provided by RefSeq]
Specifications
Specifications
| Antigen | MADCAM1 |
| Applications | ELISA, Flow Cytometry, Immunohistochemistry (PFA fixed), Western Blot |
| Classification | Monoclonal |
| Clone | 314G8 |
| Conjugate | Unconjugated |
| Description | Mouse monoclonal antibody raised against human MADCAM1. |
| Dilution | ELISA Flow Cytometry (1:10-1:100) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (10 ug/mL) Western Blot The optimal working dilution should be determined by the end user. |
| Formulation | In PBS, pH 7.4. |
| Gene Alias | MACAM1 |
| Gene Symbols | MADCAM1 |
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