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Invitrogen™ MAEL Polyclonal Antibody
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Catalog No. PIPA5115533
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100 μL
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PIPA5115533 100 μL
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Catalog No. PIPA5115533 Supplier Invitrogen™ Supplier No. PA5115533
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total Mael.

The mammalian homolog of the Drosophila protein Maelstrom is expressed in the male germline and localizes to the sex body in spermatocytes and the chromatid body in round spermatids. Similar to its expression in Drosophila, Maelstrom is a component of nuages, a germ-cell specific organelle and is thought to be essential for spermatogenesis and transposon repression during meiosis. In humans, Maelstrom has been found to be expressed only in the testis and in various cancer cell lines. Treatment of these cell lines with the demethylating agent 5'-Aza-2-Deoxycytidine significantly upregulated Maelstrom levels, indicating that its expression is regulated by DNA methylation.
TRUSTED_SUSTAINABILITY

Specifications

Antigen MAEL
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide
Gene MAEL
Gene Accession No. Q96JY0
Gene Alias 4933405K18Rik; AU019877; cancer/testis antigen 128; CT128; MAEL; maelstrom homolog; maelstrom homolog (Drosophila); maelstrom spermatogenic transposon silencer; protein maelstrom homolog; RGD1309333; RP11-102C16.1; SPATA35; spermatogenesis associated 35; testicular tissue protein Li 116
Gene Symbols MAEL
Host Species Rabbit
Immunogen A synthesized peptide derived from human MAEL(Accession Q96JY0), corresponding to amino acid residues G390-S434.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 84944
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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