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MAEL Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
SDP

Catalog No. 501735419 Shop All Proteintech Group Inc Products
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50-173-5419 150 μL
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Catalog No. 50-173-5419 Supplier Proteintech Group Inc Supplier No. 266661AP150UL
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Description

Rabbit Polyclonal Antibody

The mammalian homolog of the Drosophila protein Maelstrom is expressed in the male germline and localizes to the sex body in spermatocytes and the chromatid body in round spermatids. Similar to its expression in Drosophila, Maelstrom is a component of nuages, a germ-cell specific organelle and is thought to be essential for spermatogenesis and transposon repression during meiosis. In humans, Maelstrom has been found to be expressed only in the testis and in various cancer cell lines. Treatment of these cell lines with the demethylating agent 5′-Aza-2-Deoxycytidine significantly upregulated Maelstrom levels, indicating that its expression is regulated by DNA methylation.

Specifications

Antigen MAEL
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.33 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene MAEL
Gene Accession No. Q8BVN9, Q96JY0
Gene Alias MAEL, maelstrom homolog (Drosophila), Protein maelstrom homolog, RP11 102C16.1
Gene Symbols Mael
Host Species Rabbit
Immunogen MAEL Fusion Protein Ag24524
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 364039, 84944, 98558
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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