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Invitrogen™ MAFA Polyclonal Antibody

Catalog No. PI720262
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100 μg
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Catalog No. Quantity
PI720262 100 μg
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Catalog No. PI720262 Supplier Invitrogen™ Supplier No. 720262
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Description

Rabbit Polyclonal Antibody

These Polyclonal antibodies are of rabbit origin developed by immunizing animals with proteins or peptides. The polyclonal antibody is purified by affinity purification from the rabbit sera generated after immunizing the rabbits with a specific type of protein or peptide. The purified antibody is tested for its functionality in various relevant research applications. The antibody is developed for Research Use Only and is non-hazardous or non-infectious in nature. This antibody is predicted to react with Monkey, Mouse, Rat and Bovine.

MAFA is a transcription factor that binds RIPE3b, a conserved enhancer element that regulates pancreatic beta cell-specific expression of the insulin gene. MAFA cooperates synergistically with NEUROD1 and PDX1. Phosphorylation by GSK3 increases its transcriptional activity and is required for its ocogenic activity. Serves as an ocogene or tumor supressor depending on the cell context.
TRUSTED_SUSTAINABILITY

Specifications

Antigen MAFA
Applications ChIP Assay, Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.1% BSA, 30% glycerol and 0.09% sodium azide; pH 7.2-7.4
Gene Mafa
Gene Accession No. Q8NHW3
Gene Alias hMafA; MAF bZIP transcription factor A; MAFA; Mafa homolog; pancreatic beta-cell-specific transcriptional activator; RGD1562627; RIPE3b1; RIPE3b1 factor; Transcription factor MafA; transcription factor RIPE3b1; v-maf avian musculoaponeurotic fibrosarcoma oncogene A; v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog A; v-maf musculoaponeurotic fibrosarcoma oncogene family, protein A; v-maf musculoaponeurotic fibrosarcoma oncogene family, protein A (avian); v-maf musculoaponeurotic fibrosarcoma oncogene homolog A
Gene Symbols Mafa
Host Species Rabbit
Immunogen Peptides corresponding to Human MAFA (aa 331-343, 28-41).
Purification Method Affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 366949, 389692
Target Species Human, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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