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MafA Polyclonal Antibody, Bethyl Laboratories

Catalog No. 501571945
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50-157-1945 100 μL
50-157-1946 10 μL
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Catalog No. 50-157-1945 Supplier Bethyl Laboratories, Inc Supplier No. IHC00352
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Description

Rabbit Polyclonal Antibody

The recommended shelf life for this product is 1 year from date of receipt.

MAFA is a transcription factor that binds RIPE3b, a conserved enhancer element that regulates pancreatic beta cell-specific expression of the insulin gene. MAFA cooperates synergistically with NEUROD1 and PDX1. Phosphorylation by GSK3 increases its transcriptional activity and is required for its ocogenic activity. Serves as an ocogene or tumor supressor depending on the cell context.

Specifications

Antigen MafA
Applications Immunohistochemistry
Classification Polyclonal
Conjugate Unconjugated
Formulation TBS with 0.1% BSA and 0.09% sodium azide
Gene Mafa
Gene Accession No. Q8CF90
Gene Alias RIPE3b1, hMafA, pancreatic beta-cell-specific transcriptional activator, transcription factor MafA, transcription factor RIPE3b1
Gene Symbols Mafa
Host Species Rabbit
Immunogen Between 300 and C-term
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 378435
Target Species Mouse
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG
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