MafA Polyclonal Antibody, Bethyl Laboratories

Rabbit Polyclonal Antibody

Supplier:  Bethyl Laboratories, Inc IHC00352

Catalog No. 50-157-1945

Description

The recommended shelf life for this product is 1 year from date of receipt.

MAFA is a transcription factor that binds RIPE3b, a conserved enhancer element that regulates pancreatic beta cell-specific expression of the insulin gene. MAFA cooperates synergistically with NEUROD1 and PDX1. Phosphorylation by GSK3 increases its transcriptional activity and is required for its ocogenic activity. Serves as an ocogene or tumor supressor depending on the cell context.

Specifications

• Antigen: MafA
• Classification: Polyclonal
• Formulation: TBS with 0.1% BSA and 0.09% sodium azide
• Gene Accession No.: Q8CF90
• Gene Symbols: Mafa
• Immunogen: Between 300 and C-term
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Mouse
• Product Type: Antibody
• Isotype: IgG

• Applications: Immunohistochemistry
• Conjugate: Unconjugated
• Gene: Mafa
• Gene Alias: RIPE3b1, hMafA, pancreatic beta-cell-specific transcriptional activator, transcription factor MafA, transcription factor RIPE3b1
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 378435
• Content And Storage: 4° C
• Form: Liquid