Invitrogen™ MAFA Recombinant Rabbit Monoclonal Antibody (BLR067G)

Rabbit Recombinant Monoclonal Antibody

Supplier:  Invitrogen™ MA544326

Catalog No. PIMA544326

Description

Epitope retrieval with citrate buffer pH6.0 is recommended for FFPE cell sections.

MAFA is a transcription factor that binds RIPE3b, a conserved enhancer element that regulates pancreatic beta cell-specific expression of the insulin gene. MAFA cooperates synergistically with NEUROD1 and PDX1. Phosphorylation by GSK3 increases its transcriptional activity and is required for its ocogenic activity. Serves as an ocogene or tumor supressor depending on the cell context.

Specifications

• Antigen: MAFA
• Classification: Recombinant Monoclonal
• Concentration: 1 mg/mL
• Formulation: BBS with 0.09% sodium azide; pH 8.2
• Gene Accession No.: Q8NHW3
• Gene Symbols: Mafa
• Immunogen: Peptide representing a region between residue 125 and 175 of human MAF bZIP transcription factor A.
• Quantity: 10 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Clone: BLR067G
• Conjugate: Unconjugated
• Gene: Mafa
• Gene Alias: hMafA; MAF bZIP transcription factor A; MAFA; Mafa homolog; pancreatic beta-cell-specific transcriptional activator; RGD1562627; RIPE3b1; RIPE3b1 factor; Transcription factor MafA; transcription factor RIPE3b1; v-maf avian musculoaponeurotic fibrosarcoma oncogene A; v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog A; v-maf musculoaponeurotic fibrosarcoma oncogene family, protein A; v-maf musculoaponeurotic fibrosarcoma oncogene family, protein A (avian); v-maf musculoaponeurotic fibrosarcoma oncogene homolog A
• Host Species: Rabbit
• Purification Method: purified
• Regulatory Status: RUO
• Gene ID (Entrez): 389692
• Content And Storage: 4°C
• Form: Liquid

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov