Invitrogen™ MAFK Monoclonal Antibody (381923)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA524120

Catalog No. PIMA524120

Description

In Western blots, no cross-reactivity with recombinant human (rh) MafB or rhMafF is observed. In Western blots, prolonged film exposures may slightly detect rhMafG. Reconstitute at 0.5 mg/mL in sterile PBS.

Since they lack a putative transactivation domain, the small Mafs behave as transcriptional repressors when they dimerize among themselves. However, they seem to serve as transcriptional activators by dimerizing with other (usually larger) basic-zipper proteins and recruiting them to specific DNA-binding sites. Small Maf proteins heterodimerize with Fos and may act as competitive repressors of the NF-E2 transcription factor.

Specifications

• Antigen: MAFK
• Classification: Monoclonal
• Concentration: 0.5 mg/mL
• Formulation: PBS with 5% trehalose and No Preservative
• Gene Accession No.: O60675, Q61827
• Gene Symbols: MAFK
• Immunogen: E. coli-derived recombinant human MafK Thr2-Ser156.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG2b

• Applications: Western Blot
• Clone: 381923
• Conjugate: Unconjugated
• Gene: MAFK
• Gene Alias: AW061068; basic-leucine zipper transcription factor MafK; erythroid transcription factor NF-E2 p18 subunit; FLJ32205; MAF bZIP transcription factor K; Mafk; MGC71717; NF-E2; Nfe2u; nuclear factor erythroid-2, ubiquitous (p18); nuclear factor, erythroid derived 2, ubiquitous; P18; p18 NF-E2; transcription factor MafK; v-maf avian musculoaponeurotic fibrosarcoma oncogene family, protein K; v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog K; v-maf musculoaponeurotic fibrosarcoma oncogene family, protein K; v-maf musculoaponeurotic fibrosarcoma oncogene family, protein K (avian); v-maf musculoaponeurotic fibrosarcoma oncogene homolog K
• Host Species: Mouse
• Purification Method: Protein A/G
• Regulatory Status: RUO
• Gene ID (Entrez): 17135, 7975
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized