Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. Cell Analysis Products
  4. Cell Based Assays
  5. General Cell Based Assays
  6. MAGR302B

R&D Systems™ MagCellect Rat CD4+ T Cell Isolation Kit

Catalog No. MAGR302B
Change view
Click to view available options
Quantity:
1 Kit
1 product options available for selection
Product selection table with 1 available options. Use arrow keys to navigate and Enter or Space to select.
Catalog No. Quantity
MAGR302B 1 Kit
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 1 options available.
1 options
This item is not returnable. View return policy
Catalog No. MAGR302B Supplier R&D Systems™ Supplier No. MAGR302B
This item is not returnable. View return policy

Description

CD4 also functions as a chemotactic receptor for IL-16 and, in human, as a coreceptor for the gp120 surface glycoprotein of HIV-1

  • CD4 is a transmembrane glycoprotein that is expressed predominantly on thymocytes and a subset of mature T lymphocytes
  • It is a standard phenotype marker for the identification of T cell populations
  • CD4 is expressed along with CD8 on double positive T cells during their development in the thymus
  • Either CD4 or CD8 expression is then lost, giving rise to single positive (SP) CD4+ or CD8+ mature T cells
  • CD4+ SP cells, also known as T helper cells, further differentiate into multiple subsets of CD4+ cells including Th1, Th2, Th9, Th17,Th22, Tfh, and Treg cells which regulate humoral and cellular immunity
  • In human, CD4 is additionally expressed on macrophages, neutrophils, monocytes, NK cells, and neurons and glial cells in the brain
  • CD4 binds directly to MHC class II molecules on antigen presenting cells
  • This interaction contributes to the formation of the immunological synapse which is focused around the TCR-MHC class II-antigenic peptide interaction

Specifications

Content And Storage Store the unopened product at 2°C to 8°C. Do not use past expiration date.
Quantity 1 Kit
Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.