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  6. Epredia™ Lab Vision™ MAGE-1 Ab-6, Mouse Monoclonal Antibody

Epredia™ Lab Vision™ MAGE-1 Ab-6, Mouse Monoclonal Antibody

Catalog No. MS1836R1 Shop All Epredia Products
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7 mL
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Catalog No. Quantity Form
MS1836R1 1 mL Prediluted
MS1836S0 100 μL Concentrated
MS1836S1 500 μL Concentrated
MS1836S 1 mL Concentrated
MS1836R7 7 mL Prediluted
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Catalog No. MS1836R1 Supplier Epredia™ Supplier No. MS1836R1

Description

Ideal for Immunohistochemistry (Formalin/paraffin), Epredia™ MAGE-1 Ab-6, Mouse Monoclonal Antibody provides accurate, reproducible results.

Human malignant neoplasms carry rejection antigens that are recognized by the patients' autologous, tumor-directed and specific, cytolytic, CD8+ T lymphocyte clones (CTL). An important group of antigens is coded by the MAGE family of genes. It was identified that melanomas and primary glial brain tumors express common melanoma associated antigens (MAAs). Because MAGE-1 is expressed on a significant proportion of human neoplasms of various histological types (melanoma, brain tumors of glial origin, neuroblastoma, non-small cell lung cancer, breast, gastric, colorectal, ovarian, renal cell carcinomas) and not on normal tissues, the encoded antigen may serve as a marker of early detection and target for cancer immunotherapy

Host Species: Mouse

Clone: 6C1

Isotype: IgG2a

Species Reactivity: Human. Others not known.

Epitope: Not determined

Immunogen: Full-length recombinant human MAGE-1 protein

Molecular Weight: 42-46kDa

Positive Control: Hepatocellular CA, normal testis

Cellular Localization: Cytoplasmic, occasionally nuclear

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)

Note:

USA: RUO; Int'l: RUO

Specifications

Antigen MAGE-1 Ab-6
Applications Immunohistochemistry (Paraffin)
Classification Monoclonal
Clone 6C1
Conjugate Unconjugated
Host Species Mouse
Immunogen Full length recombinant human MAGE-1 protein
Quantity 1 mL
Regulatory Status RUO
Research Discipline Cancer and Tumor Biology
Primary or Secondary Primary
Target Species Human
Form Prediluted
Isotype IgG2a
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