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MAGE 1 Antibody (MA454), Alexa Fluor™ 350, Novus Biologicals™
SDP

Catalog No. NP233094A30 Shop All R&D Systems Products
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NP233094A30 0.1 mL
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Catalog No. NP233094A30 Supplier Novus Biologicals Supplier No. NBP233094AF350
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Description

Mouse Monoclonal Antibody

MAGE 1 Monoclonal specifically detects MAGE 1 in Human, Rat, Canine samples. It is validated for ELISA.

Specifications

Antigen MAGE 1
Applications ELISA
Classification Monoclonal
Clone MA454
Conjugate Alexa Fluor 350
Dilution ELISA
Formulation 50 mM sodium borate with 0.05% sodium azide
Gene Alias Antigen MZ2-E, Cancer/testis antigen 1.1, cancer/testis antigen family 1, member 1, CT1.1melanoma antigen family A 1, MAGE-1 antigen, MAGE1A, MAGE1melanoma antigen MAGE-1, melanoma antigen family A, 1 (directs expression of antigen MZ2-E), melanoma-associated antigen 1, melanoma-associated antigen MZ2-E, MGC9326
Gene Symbols MAGEA1
Host Species Mouse
Immunogen Recombinant full-length human MAGE 1 protein (Uniprot: P43355)
Purification Method Protein A or G purified
Quantity 0.1 mL
Primary or Secondary Primary
Gene ID (Entrez) 4100
Test Specificity Recognizes a protein of 42-46kDa, identified as MAGE-1. This monoclonal antibody does not cross-react with MAGE-2, -3, -4, -6 -9, -10, -or -12 protein. Human malignant neoplasms carry rejection antigens that are recognized by the patients' autologous, tumor directed and specific, cytolytic, CD8+ T lymphocyte clones (CTL). The MAGE family of genes codes an important group of antigens. It was identified that melanomas and primary glial brain tumors express common melanoma associated antigens (MAAs). Because MAGE-1 is expressed on a significant proportion of human neoplasms of various histological types (melanoma, brain tumors of glial origin, neuroblastoma, non-small cell lung cancer, breast, gastric, colorectal, ovarian, renal cell carcinomas) and not on normal tissues, the encoded antigen may serve as a marker of early detection and target for cancer immunotherapy.
Target Species Human, Rat, Canine
Content And Storage Store at 4°C in the dark.
Isotype IgG1 κ
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