MAGE-1 Rabbit anti-Human, Polyclonal, Bioss

Catalog No.	Quantity
50-198-0531	100 μL

Catalog No. 50-198-0531 Supplier Bioss Supplier No. BS0817R

Description

Rabbit Polyclonal Antibody

Human malignant neoplasms carry rejection antigens that are recognized by the patients′ autologous, tumor directed and specific, cytolytic, CD8+ T lymphocyte clones (CTL). An important group of antigens is coded by the MAGE family of genes. It was identified that melanoma associated with antigens (MAAs). Because MAGE-1 is expressed on a significant proportion of human neoplasms of various hisological tyoes (melanoma, brain tumors of glial origin, neuroblastoma, non-small cell lung cancer, breast, gastric, colorectal, ovarian, renal cell carcinomas) and not on normal tissues, the encoded antigen may serve as a marker of early detection and target for cancer immunotherapy.

Specifications

• Antigen: MAGE-1
• Applications: Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Classification: Polyclonal
• Concentration: 1 μg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
• Gene: MAGEA1
• Gene Accession No.: P43355
• Gene Alias: Antigen MZ2-E; Cancer/testis antigen 1.1; cancer/testis antigen family 1, member 1; CT1.1; MAGE family member A1; MAGE1; MAGE-1 antigen; MAGE1A; MAGEA1; Mage-a1; melanoma antigen family A 1; melanoma antigen family A, 1; melanoma antigen family A, 1 (directs expression of antigen MZ2-E); melanoma antigen family A1; melanoma antigen MAGE-1; melanoma antigen, family A, 1; Melanoma-associated antigen 1; melanoma-associated antigen MZ2-E
• Gene Symbols: MAGEA1
• Host Species: Rabbit
• Immunogen: KLH conjugated synthetic peptide derived from human MAGE-1.
• Purification Method: Protein A
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 4100
• Target Species: Human
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG