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Invitrogen™ MAGE1 Monoclonal Antibody (E22-11B2-E9)
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Catalog No. PIMA191067
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500 μL
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PIMA191067 500 μL
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Catalog No. PIMA191067 Supplier Invitrogen™ Supplier No. MA191067
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Description

Mouse Monoclonal Antibody

Recommended positive controls: Colo32 cells..

Human malignant neoplasms carry rejection antigens that are recognized by the patients' autologous, tumor directed and specific, cytolytic, CD8+ T lymphocyte clones (CTL). An important group of antigens is coded by the MAGE family of genes. It was identified that melanoma associated with antigens (MAAs). Because MAGE-1 is expressed on a significant proportion of human neoplasms of various hisological tyoes (melanoma, brain tumors of glial origin, neuroblastoma, non-small cell lung cancer, breast, gastric, colorectal, ovarian, renal cell carcinomas) and not on normal tissues, the encoded antigen may serve as a marker of early detection and target for cancer immunotherapy.
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Specifications

Antigen MAGE1
Applications Western Blot
Classification Monoclonal
Clone E22-11B2-E9
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.2% BSA and 0.09% sodium azide; pH 7.4
Gene MAGEA1
Gene Accession No. P43355
Gene Alias antigen MZ2-E; antigen p97 (melanoma associated) identified by monoclonal antibodies 133.2 and 96.5; cancer/testis antigen 1.1; cancer/testis antigen family 1, member 1; CD228; CT1.1; mage 1; MAGE family member A1; MAGE1; mage-1; MAGE-1 antigen; MAGE1A; MAGEA1; Mage-a1; MAP97; melanoma antigen family A 1; melanoma antigen family A, 1; melanoma antigen family A, 1 (directs expression of antigen MZ2-E); melanoma antigen family A1; melanoma antigen MAGE-1; melanoma antigen, family A, 1; melanoma-associated antigen 1; melanoma-associated antigen MZ2-E; Melanoma-associated antigen p97; melanoma-associated antigen p97, isoform 2; melanotransferrin; MELTF; membrane-bound transferrin-like protein; Mfi2; MTf; MTF1
Gene Symbols MAGEA1
Host Species Mouse
Immunogen Recombinant full length protein (Human).
Purification Method Protein A
Quantity 500 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 4100
Target Species Human
Content And Storage 4°C, do not freeze
Product Type Antibody
Form Liquid
Isotype IgG2a
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