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Invitrogen™ MAGE1 Recombinant Rabbit Monoclonal Antibody (9Y6K1)
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Catalog No. PIMA537821
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100 μL
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PIMA537821 100 μL
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Catalog No. PIMA537821 Supplier Invitrogen™ Supplier No. MA537821
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Description

Rabbit Recombinant Monoclonal Antibody

Positive Samples: HeLa, A-549, A375, Mouse lung, Mouse testis Immunogen sequence: VMIAMEGGHA PEEEIWEELS VMEVYDGREH SAYGEPRKLL TQDLVQEKYL EYRQVPDSDP ARYEFLWGPR ALAETSYVKV LEYVIKVSAR VRFFFPSLRE AALREEEEGV.

Human malignant neoplasms carry rejection antigens that are recognized by the patients' autologous, tumor directed and specific, cytolytic, CD8+ T lymphocyte clones (CTL). An important group of antigens is coded by the MAGE family of genes. It was identified that melanoma associated with antigens (MAAs). Because MAGE-1 is expressed on a significant proportion of human neoplasms of various hisological tyoes (melanoma, brain tumors of glial origin, neuroblastoma, non-small cell lung cancer, breast, gastric, colorectal, ovarian, renal cell carcinomas) and not on normal tissues, the encoded antigen may serve as a marker of early detection and target for cancer immunotherapy.
TRUSTED_SUSTAINABILITY

Specifications

Antigen MAGE1
Applications ELISA, Western Blot
Classification Recombinant Monoclonal
Clone 9Y6K1
Concentration 0.52 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene MAGEA1
Gene Accession No. P43355
Gene Alias antigen MZ2-E; antigen p97 (melanoma associated) identified by monoclonal antibodies 133.2 and 96.5; cancer/testis antigen 1.1; cancer/testis antigen family 1, member 1; CD228; CT1.1; mage 1; MAGE family member A1; MAGE1; mage-1; MAGE-1 antigen; MAGE1A; MAGEA1; Mage-a1; MAP97; melanoma antigen family A 1; melanoma antigen family A, 1; melanoma antigen family A, 1 (directs expression of antigen MZ2-E); melanoma antigen family A1; melanoma antigen MAGE-1; melanoma antigen, family A, 1; melanoma-associated antigen 1; melanoma-associated antigen MZ2-E; Melanoma-associated antigen p97; melanoma-associated antigen p97, isoform 2; melanotransferrin; MELTF; membrane-bound transferrin-like protein; Mfi2; MTf; MTF1
Gene Symbols MAGEA1
Host Species Rabbit
Immunogen A synthetic peptide corresponding to a sequence within amino acids 200-309 of human MAGE-1/MAGE1A (P43355).
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 17137, 4100
Target Species Human, Mouse
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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