Invitrogen™ MAGEA10 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA551897

Catalog No. PIPA551897

Description

Immunogen sequence: TSSSFPSSFP SSSSSSSSSC YPLIPSTPEE VSADDETPNP PQSAQIACSS PSVVASLPLD QSDEGSSSQK EESPSTLQVL PDSESLPRSE IDEKVTDLVQ FLLFKYQ Highest antigen sequence identity to the following orthologs: Mouse - 40%, Rat - 37%.

MAGEA10 is a member of the MAGEA gene family. The members of this family have their entire coding sequences located in the last exon, and the encoded proteins show 50 to 80% sequence identity between each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are expressed at a high level in a number of tumors of various histologic types, and are silent in normal tissues with the exception of testis and placenta. The MAGEA genes are clustered on chromosome Xq28. They may be implicated in some hereditary disorders, such as dyskeratosis congenita.

Specifications

• Antigen: MAGEA10
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: MAGEA10
• Gene Alias: cancer/testis antigen 1.10; cancer/testis antigen family 1, member 10; CT1.10; MAGE family member A10; MAGE10; MAGE-10 antigen; MAGEA10; melanoma antigen family A, 10; melanoma antigen family A10; melanoma-associated antigen 10; RGD1563693
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 4109
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 0.1 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: P43363
• Gene Symbols: MAGEA10
• Immunogen: Recombinant protein corresponding to Human MAGEA10. Recombinant protein control fragment (Product #RP-92198).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG