Invitrogen™ MAGEA11 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA522114

Catalog No. PIPA522114

Description

Recommended positive controls: A431, H1299. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

MAGEA11 is a member of the MAGEA gene family. The members of this family have their entire coding sequences located in the last exon, and the encoded proteins show 50 to 80% sequence identity between each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are expressed at a high level in a number of tumors of various histologic types, and are silent in normal tissues with the exception of testis and placenta. The MAGEA genes are clustered on chromosome Xq28. They may be implicated in some hereditary disorders, such as dyskeratosis congenita.

Specifications

• Antigen: MAGEA11
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: MAGEA11
• Gene Alias: cancer/testis antigen 1.11; cancer/testis antigen family 1, member 11; CT1.11; MAGE family member A11; MAGE11; MAGE-11; MAGE-11 antigen; MAGEA11; MAGEA-11; melanoma antigen family A, 11; melanoma antigen family A11; melanoma-associated antigen 11
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 4110
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: P43364
• Gene Symbols: MAGEA11
• Immunogen: Synthetic peptide corresponding to a region within amino acids 78 and 173 of MAGEA11 (Uniprot ID#P43364).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG