Invitrogen™ MAGEA11 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA599769

Catalog No. PIPA599769

Description

Antibody detects endogenous levels of total MAGEA11.

MAGEA11 is a member of the MAGEA gene family. The members of this family have their entire coding sequences located in the last exon, and the encoded proteins show 50 to 80% sequence identity between each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are expressed at a high level in a number of tumors of various histologic types, and are silent in normal tissues with the exception of testis and placenta. The MAGEA genes are clustered on chromosome Xq28. They may be implicated in some hereditary disorders, such as dyskeratosis congenita.

Specifications

• Antigen: MAGEA11
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: MAGEA11
• Gene Alias: cancer/testis antigen 1.11; cancer/testis antigen family 1, member 11; CT1.11; MAGE family member A11; MAGE11; MAGE-11; MAGE-11 antigen; MAGEA11; MAGEA-11; melanoma antigen family A, 11; melanoma antigen family A11; melanoma-associated antigen 11
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 302845, 4110
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: P43364
• Gene Symbols: MAGEA11
• Immunogen: A synthesized peptide derived from human MAGEA11(Accession P43364), corresponding to amino acid residues P388-V429.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Rat
• Product Type: Antibody
• Isotype: IgG