Invitrogen™ MAGEA2 Monoclonal Antibody (1B1)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA524545

Catalog No. PIMA524545

Description

Peptide Sequence: MPLEQRSQHC KPEEGLEARG EALGLVGAQA PATEEQQTAS SSSTLVEVTL GEVPAADSPS PPHSPQGASS FSTTINYTLW RQSDEGSSNQ EEEGPRMFPD LESEFQAAIS RKMVELVHFL LLKYQAREPV TKAEMLESVL RNCQDFFPVI FSKASEYLQL VFGIEVVEVV PISHLYILVT CLGLSYDGLL GDNQVMPKTG LLIIVLAIIA IEGDCAPEEK IWEELSMLEV FEGREDSVFA HPRKLLMQDL VQENYLEYRQ VPGSDPACYE FLWGPRALIE TSYVKVLHHT LKIGGEPHIS YPPLHERALR EGEE.

MAGEA2 is a member of the MAGEA gene family. The members of this family have their entire coding sequences located in the last exon, and the encoded proteins show 50 to 80% sequence identity between each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are expressed at a high level in a number of tumors of various histologic types, and are silent in normal tissues with the exception of testis and placenta. The MAGEA genes are clustered on chromosome Xq28. They may be implicated in some hereditary disorders, such as dyskeratosis congenita. This gene has two identical copies at different loci.

Specifications

• Antigen: MAGEA2
• Classification: Monoclonal
• Concentration: 0.43 mg/mL
• Formulation: PBS with no preservative; pH 7.4
• Gene Accession No.: P43356
• Gene Symbols: MAGEA2
• Immunogen: MAGEA2 (AAH63681, 1 a.a. ~ 314 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2a κ

• Applications: ELISA, Western Blot, Immunocytochemistry
• Clone: 1B1
• Conjugate: Unconjugated
• Gene: MAGEA2
• Gene Alias: Cancer/testis antigen 1.2; cancer/testis antigen family 1, member 2; CT1.2; MAGE family member A2; MAGE2; MAGE-2 antigen; MAGEA2; MAGEA2A; MAGEA2B; melanoma antigen 2; melanoma antigen family A, 2; melanoma antigen family A2; melanoma-associated antigen 2; MGC131923
• Host Species: Mouse
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 4101
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid