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MAGEA2 Mouse anti-Human, Clone: 1B1, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA524545

Catalog No. PIMA524545


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Description

Description

Peptide Sequence: MPLEQRSQHC KPEEGLEARG EALGLVGAQA PATEEQQTAS SSSTLVEVTL GEVPAADSPS PPHSPQGASS FSTTINYTLW RQSDEGSSNQ EEEGPRMFPD LESEFQAAIS RKMVELVHFL LLKYQAREPV TKAEMLESVL RNCQDFFPVI FSKASEYLQL VFGIEVVEVV PISHLYILVT CLGLSYDGLL GDNQVMPKTG LLIIVLAIIA IEGDCAPEEK IWEELSMLEV FEGREDSVFA HPRKLLMQDL VQENYLEYRQ VPGSDPACYE FLWGPRALIE TSYVKVLHHT LKIGGEPHIS YPPLHERALR EGEE

MAGEA2 is a member of the MAGEA gene family. The members of this family have their entire coding sequences located in the last exon, and the encoded proteins show 50 to 80% sequence identity between each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are expressed at a high level in a number of tumors of various histologic types, and are silent in normal tissues with the exception of testis and placenta. The MAGEA genes are clustered on chromosome Xq28. They may be implicated in some hereditary disorders, such as dyskeratosis congenita. This gene has two identical copies at different loci.
Specifications

Specifications

MAGEA2
Monoclonal
Unconjugated
MAGEA2
Liquid
MAGEA2
MAGEA2 (AAH63681, 1 a.a. ∽ 314 a.a) full-length recombit protein with GST tag. MW of the GST tag alone is 26 KDa.
Protein A
RUO
Antibody
Monoclonal
Human
ELISA, Immunocytochemistry, Immunofluorescence, Western Blot
1B1
PBS with no preservative; pH 7.4
P43356
Melanoma antigen family A, 2, CT1.2, MAGE2, MAGEA2A, MAGEA2B, MGC131923
Mouse
IgG2a, kappa
100 μg
-20° C
Primary
4101
Documents
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