Invitrogen™ MAGEB18 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA561161

Catalog No. PIPA561161

Description

Immunogen sequence: STTNAIAPVS CSSNEGASSQ DEKSLGSSRE AEGWKEDPLN KKVVSLVHFL LQKYETKEPI T Highest antigen sequence identity to the following orthologs: Mouse - 38%, Rat - 41%.

The melanoma-associated antigen (MAGE) family consists of a number of antigens recognized by cytotoxic T lymphocytes. The MAGE genes were initially isolated from different kinds of tumors and, based on their virtually exclusive tumor-specific expression in adult tissues, they have been used as targets for cancer immunotherapy. MAGE genes encode for tumor-rejection antigens that are expressed in tumors of different histologic types and in normal testis and placenta. MAGE-B18 (melanoma-associated antigen B18) is a 343 amino acid protein that contains one MAGE domain and may be involved in tumorigenesis. The gene encoding MAGE-B18 maps to human chromosome X, which contains nearly 153 million base pairs and houses over 1,000 genes.

Specifications

• Antigen: MAGEB18
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: MAGEB18
• Gene Alias: MAGBI; MAGE family member B18; MAGEB18; MAGE-B18 antigen; melanoma antigen family B, 18; melanoma antigen family B18; melanoma-associated antigen B18
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 286514
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.05 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q96M61
• Gene Symbols: MAGEB18
• Immunogen: Recombinant protein corresponding to Human MAGEB18. Recombinant protein control fragment (Product #RP-95711).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG