Invitrogen™ MAGI2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA599245

Catalog No. PIPA599245

Description

Antibody detects endogenous levels of total MAGI2.

Seems to act as scaffold molecule at synaptic junctions by assembling neurotransmitter receptors and cell adhesion proteins. May play a role in regulating activin-mediated signaling in neuronal cells. Enhances the ability of PTEN to suppress AKT1 activation. Plays a role in nerve growth factor (NGF)-induced recruitment of RAPGEF2 to late endosomes and neurite outgrowth. Florindo C.S., Submitted (JUL-2003) to the EMBL/GenBank/DDBJ databases. The MGC Project Team, Genome Res. 14:2121-2127(2004). Devroe E., J. Biol. Chem. 279:24444-24451(2004).

Specifications

• Antigen: MAGI2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: MAGI2
• Gene Alias: activin receptor interacting protein 1; activin receptor-interacting protein 1; Acvri1; ACVRINP1; Acvrip1; AIP1; AIP-1; ARIP1; Atrophin-1-interacting protein 1; atrophin-1-interacting protein A; KIAA0705; MAGI2; MAGI-2; membrane associated guanylate kinase, WW and PDZ domain containing 2; membrane-associated guanylate kinase inverted 2; Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2; mKIAA0705; Sscam; S-SCAM; Synaptic-scaffolding molecule
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 113970, 50791, 9863
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: O88382, Q86UL8, Q9WVQ1
• Gene Symbols: MAGI2
• Immunogen: A synthesized peptide derived from human MAGI2(Accession Q86UL8), corresponding to amino acid residues E235-E285.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov