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MAGI3 Polyclonal Antibody, Bethyl Laboratories

Catalog No. 501569766
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Catalog No. Quantity
50-156-9766 20 μL
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Catalog No. 50-156-9766 Supplier Bethyl Laboratories, Inc Supplier No. A305190AT
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Description

Rabbit Polyclonal Antibody

The recommended shelf life for this product is 1 year from date of receipt.

Membrane-associated guanylate kinase with inverted orientation (MAGI3) is a novel, 130 kDa guanylate kinase which is part of a family of multi-PDZ domain containing guanylate kinases. These guanylate kinases are localized to epithelial cell tight junctions. MAGI3 and PTEN/MMAC cooperate to modulate the kinase activity of AKT/protein kinase B (PKB). MAGI3 positions the PTEN/MMAC phosphatase to specific subcellular locations that are involved with the regulation of cell proliferation and survival. MAGI3, as well as other proteins in this family, are made up of an N-terminal guanylate kinase domain, followed by a WW domain, named for two conserved tryptophan residues and first identified as two repeats in mouse YAP65, which is them followed by 5 PDZ domains.

Specifications

Antigen MAGI3
Applications Western Blot
Classification Polyclonal
Conjugate Unconjugated
Formulation TBS with 0.1% BSA and 0.09% sodium azide
Gene MAGI3
Gene Accession No. Q5TCQ9
Gene Alias Slipr
Gene Symbols MAGI3
Host Species Rabbit
Immunogen Between 1425 and 1475
Purification Method Antigen affinity chromatography
Quantity 20 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 260425
Target Species Human
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG
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